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Date:   10 January, 2010  
Focus: Small animals - dogs, cats, hamsters, guinea pig & rabbits.

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ANAESTHESIA & SURGERY
GIANT RABBIT AND GUINEA PIG

Dr Sing Kong Yuen, BVMS (Glasgow), MRCVS
First written: Dec 11, 2009. Updated: Jan 10, 2010

 
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Giant Rabbit Neutering

The vast majority of Singapore pet owners keep small rabbits of around 2-3 kg. So my staff quoted the normal prices of $75.00 for neutering of a rabbit. A price list is displayed prominently at the reception. It says: "Castration, rabbit, $75.00". No weight of the rabbit was written down. So, my receptionist referred to the list and quoted accordingly.

However, a giant rabbit was presented after the owner phoned for a quotation. Unfortunately, my staff had never thought of asking its weight, unlike the case for dog neutering. A Giant Fleming Rabbit of 5.2 kg turned up. He was extremely hyperexcitable. This type of temperament is a high anaesthetic risk.
 
METHOD 1.
One method is to use injectable anaesthesia of zoletil IM, 5 minutes later, give domitor IV via the ear vein.
However, this method seems to be unsuitable as restraint and injection causes the rabbit to move a lot.

Zoletil 50 0.2 ml IM
Waited 15 minutes
Wanted to give Domitor 0.2 ml IV, ear vein.
Still struggling. Abandoned this method in favour of Method 2.
METHOD 2
Zoletil 50 0.2 ml IM given. In around 7 minutes, the rabbit staggers and by the 15th minute, the rabbit was recumbent.

However it exhibited excitation when the ear vein was pricked and moved away.

So, I used isoflurane 5% gas by mask.
Isoflurane gas - mask - maintenance at 0.5% - 1% was excellent.  The rabbit was neutered without problems.
METHOD 3
Xylazine IM, Ketamine IM is another method I used for smaller rabbits of around 2 kg. Isoflurane Gas top up may be necessary.
This Giant Rabbit recovered after 30 minutes and went home. Method 2 is the best method for me but each vet has his own preferences. 


Guinea Pig Neutering
In a 4-month-old, 700-gram male Guinea Pig I neutered recently, Zoletil 50 0.1 ml IM was given. Then a few seconds of isoflurane gas at 1-2% provided excellent surgical anaesthesia when the guinea pig moved. The guinea Pig woke up within 1 minute after neutering was completed.

As rabbits and guinea pigs are not starved 10 hours prior to anaesthesia and surgery, unlike dogs, I neutered this guinea pig 4 hours after the young lady owner brought him in for neutering to prevent breeding. "It is much safer to neuter than to spay the guinea pig," the young girl told me. "You are correct," I replied. "Spaying takes a much longer time and require internal access inside the abdomen." 

After Zoletil injection, a copious amount of yellowish-brown fluid came out of the guinea pig's mouth. This appeared to be "vomitus". His mouth was cleaned before the gas mask was applied. This could be a side effect of Zoletil injection. 
 

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Be Kind To Pets
Veterinary Education
Project 2010-0002

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